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Vol.7 No.4 – 5: Evaluation of the anticancer activity of dipyridamole and Imatinib mesylate compounds against breast cancer cell line and related biochemical and genetic changes

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By: Rania A. El-Leithy1, Aly F. Mohamed2, Asmaa A. EL-refaay1, Mohamed M. Omran1, * 1Chemistry Department, Faculty of Science, Helwan University, Cairo, Egypt 2Former Head of R&D Sector, The Holding Company for Production of Vaccines, Sera and Drugs (VACSERA), Giza, Egypt Abstract Imatinib mesylate and dipyridamole were antineoplastic targeted chemotherapeutic agents, and it is here […]

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Vol.7 No.4 – 4: Therapeutic Role of Quercetin against Experimentally Induced Hepatocellular Carcinoma in Female Albino Rats and their offspring

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By: Asma R Abdeltawab1, Hassan I.H Elsyyad2, Karoline K.Abdelaziz1, Abd El-Fattah B. M. El-Beltagy1* 1, Zoology Department, Faculty of Science, Damanhour University, Damanhour, Egypt 2Zoology Department, Faculty of Science, Mansoura University, Mansoura, Egypt Abstract Aim:  To evaluate the potential role of quercetin against N-methyl nitrosourea (MNU)-induced hepatocellular carcinoma (HCC) in pregnant rats and their offspring. […]

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Vol.7 No.4 – 3:Molecular and Biochemical Studies on Some Natural Compounds and Their Effect on the Streptozotocin-induced Diabetic Rats and Their Role in Treatment

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By: Adel Abaskharon Guirgis1, Dawoud Fakhry Habib2, Hanan Hanna3 and Ramy Abosaif Mahmoud1 1Molecular Biology Department, Genetic Engineering &Biotechnology Research Institute University of Sadat City, Egypt 2 Clinical Biochemistry Department, National Research Centre (NRC), Egypt 3 Chemical Pathology Department, Faculty of Physical Therapy, Pharos University in Alexandria, Egypt Abstract Background: The number of individuals with […]

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Vol.7 No.4 – 2:Diagnostic values of a model based on B-type natriuretic peptide, C reactive protein, and neutrophil-lymphocyte ratio for diagnosis of diabetic heart diseases patients

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By: Mohamed M. Omran1*, Yassmin Taha2, Mohamed Kadry3, Fathy M. Eltaweel2, Tarek M. Emran4 1 Chemistry Department, Faculty of Science, Helwan University, Cairo, Egypt. 2 Chemistry Department, Faculty of Science, Damietta University, Egypt 3Laboratory Department, Gamasa Central Hospital, Gamasa, Egypt 4Clinical Pathology Department, Faculty of Medicine, Al-Azhar University, New Damietta; Egypt Abstract Background: People with […]

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Vol.7 No.4 – 1: Antioxidant effect of vitamin E on diphenylamine-induced hepato-renal oxidative stress and structural changes in rat fetuses

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By: Hend Tarek El-Borm Zoology Department-Faculty of Science-Menoufia University, Egypt Abstract To date, studies on the effects of prenatal exposure to diphenylamine on developing fetuses are sparse. Therefore, further investigation is required to determine the potential prenatal hazard of this compound and to introduce possible treatment for these hazards. This study aimed to assess the […]

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