Vol.2 No.12 – 7 : Evaluation of Health Centers Laboratory Results for Schistosoma haematobium Infection in El-Fayoum Governorate, Egypt

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By : Ahmed Abdelhalim Yameny

Society of Pathological Biochemistry and Hematology, Egypt

Ahmed A. Yameny (Email: dr.ahmedyameny@yahoo.com)

Abstract

Background : Logically ,successful treatment requires correct diagnosis based on the accuracy , reproducibility, and interpretability of investigations and examinations. The mission of health laboratory services is to provide high quality services in the right place and at the right time in respect of the needs of patients, the community  health staff including not only clinicians but also epidemiologist and environmental sanitarians. Quality is the degree to which care services influence the probability of optimal patient outcomes .” American Medical Association, 1991. Quality is never an accident . Research objective : To assess the quality of results presented  by health centers laboratories, for diagnosis of  S.haematobium in El-Fayoum Governorate. Subjects and methods: Across -sectional study was carried . This study was carried out in Ministry of  Health Laboratory Centers,in  El- Fayoum Governorate. A list of health centers was obtained from Ministry of Health (MOH). Ten Health Laboratories  were included in this study : Two central laboratories (Control Laboratory and Evaluation Laboratory)  and eight laboratories in eight  centers were chosen randomly from the list , from each laboratory 100 random urine samples were obtained and total sample size was 1000 urine samples . Results: In all centers the number of positive cases were lower than that detected by the study except in lab.1(El-Hadka health centerlaboratory), it detect one false positive case. The case was had a red blood cells in urine.And lab. No.9,(El-Sadeek primary school laboratory), there was no positive cases either by the researcher or the health center laboratories, and the total percentage of positive cases detected by health center laboratories was 67.1 % in relation to that detected by researcher.
Conclusion and recommendations : In all health centers laboratories the number of positive cases were lower than that detected by the researcher, and the total percentage of positive cases detected by health center laboratories was 67.1 % in relation to that detected by researcher. So using of Nuclepore membrane filteration technique is important for diagnosis of S.haematobium and continuous training for health centre laboratories staff is very important.

Evaluation of Health Centers Laboratory Results for Schistosoma haematobium Infection in El-converted

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Vol.2 No.12 -6 : Effect of fast neutrons-irradiated diets on liver structure and function of male albino rats

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By : Samir A. Nassar , Mahmoud R. Mahmoud , Magda S. Hanafy and Hagar A. Khalaf

Abstract

Presently, there is a growing need for the technology of food irradiation since it provides an effective process in food preservation and quality improvement . Accordingly, this study was designed to investigate the effects of fast neutron- irradiated wheat grains on the structure and function of the liver of albino rats. . Rats were categorized into two main groups (G1 & G2 ) ,40 animals for each. Each group was subdivided equally to four subgroups ( A,B,C&D for G1 and AA,BB,CC&DD for G2). A and AA served as control animals for G1 and G2 respectively and given non-irradiated diets ,while B,C&D were given irradiated diets at three different fluencies of fast neutrons;4.3×105 ,2.0×106 and 1.4×107 n/Cm2 respectively .But ,BB,CC and DD were given a diet of irradiated wheat of the second generation ( harvested from cultivation of the irradiated grains of the first generation ) at the same previous fluencies. Serum albumin and total protein, biochemical markers of liver function ( ALP, ALT and AST ) and the histopathological alterations of liver would be tested. Rresults of the present work highlight the detectable effect of irradiated wheat grains by the moderate ( 106 ) and the highest ( 107 ) fluencies of fast neutrons on albumin and total protein concentrations ( as indices of liver synthetic capacity). However the lowest (105) fluency exerted no detectable effect. The application of feeding with grains of the 2nd. generation on G2 experimental subgroups ( BB, CC & DD ) recorded a slight increase did not approaching a significant value ( p > 0.05 ) concerning albumin and total protein levels, in all treated animals Concerning the enzyme activities of alkaline phosphatase ( ALP ) and transaminases ( ALT & AST ) , they recorded minor fluctuations between the positive and negative range in the exposed animals of both groups ( G1 & G2) as compared to controls . But , these little differences did not approaching a significant record except for ALP inBB subgroup of G2 . On histopathological examination of liver tissue , sporadic spontaneous lesions , known to occur in rats , were the only findings , with no specific relation to the studied stress factor .Therefore , it can be concluded that fast neutron-irradiated diets does not cause changes of any toxicological significance in experimental animals , at the conditions of the current experiment , in spite of minor changes in biochemical parameters . But , it is necessary to demonstrate the safety of radiationprocessed food in case of human consumption.

6. Effect of fast neutrons-irradiated diets on liver structure and function of male albino rats

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