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Vol.10 No.1 – 5: Investigate the impact of probiotics of lactic acid bacteria obtained from various local sources on some pathogenic bacteria.

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Hasanain Qasim Mezaal Al-kaabi1, Rahman Laibi Chelab1

1 Department of Biology, College of Education for Pure Sciences, University of Thi-Qar, 64001, Iraq.

ABSTRACT

Probiotics play a crucial role in fighting infectious diseases by significantly impacting their control. They possess the capacity to lower the frequency of contagious illnesses, potentially lessening the dependence on antibiotics and helping to alleviate the development of bacteria that are resistant to various medications. Besides, they hold substantial importance in the realm of food. The objective of this research was to isolate various strains of lactic acid bacteria (LAB) from diverse sources and explore their capabilities in laboratory settings. The efficacy of probiotic strains against some harmful bacteria was assessed through both the agar diffusion method and the agar spot method. Additionally, their resilience under conditions resembling the stomach and intestinal environment, their capacity for auto-aggregation, and antibiofilm were also examined. Our findings suggest that the isolated strains displayed differing levels of probiotic effectiveness, with the HR3 strain, identified as Lactiplantibacillus plantarum, demonstrating notable excellence in this regard.

Investigate the impact of probiotics of lactic acid bacteria obtained from various local sources on some pathogenic bacteria

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Vol.8 No.3 – 6:Antimicrobial activity of Lactobacillus acidophilus against pathogenic Escherichia coli isolated from diarrhea patients

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By: Furqan Majid Kadhum

Department of Medical Optics Techniques, Al-Farabi University College, Baghdad, IRAQ

Abstract:

Lactobacillus acidophilus represents a probiotic bacterium that may be found in the mouth, gut, and vaginal canal. Lactobacillus acidophillus may help to relieve diarrhea, bloating, and cramps caused by bacteria that may cause everything from diarrhea to life-threatening colon inflammation. Escherichia coli (hencefourth E. Coil) bacteria are found in healthy people’s intestines as natural flora. Only a very small percentage, like the E. coli O157:H7 variety, can lead to severe stomach discomfort, bloody diarrhea, and vomiting; the rest of the E. coli variety is harmless.

Antimicrobial activity of Lactobacillus acidophilus against pathogenic Escherichia coli isolated from diarrhea patients (1)

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Vol.2 No.1 -3 : Studies on the antibacterial effect of probiotics and prebiotics against Staphylococcus aureus and Pseudomonas aeruginosa.

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By : Shaaban,M.T1., Hussien ,M.Z2., Allam N.G.3, Moustafa H.H.1

Abstract

The influences of Lactobacillus acidophilus, Bifidobacterium bifidus and Streptococcus thermophiles ( probiotics mixture) were studied against Staphylococcus aureus and Pseudomonas aeruginosa.The ethanolic precipitate of the probiotics mixture revealed antimicrobial activity against Staphylococcus aureus and assayed qualitatively by GC-Mass spectrum as it partially identified as carbohydrate substances, Antimicrobial activities of the used probiotics and prebiotics against S. aureus were studied in vitro referring to commercial used antibiotics, To investigate the protective efficiency of probiotics mixture and their prebiotics against S. aureus infection in mice, acomparative studies have been conducted and the success of treatment or prevention had been measured through detection of Liver enzymes (Aspartate transaminase (AST) and Alanin transaminase (ALT) , bacterial colony count in target organs (liver and lung ), histological changes occurred in liver and intestine and immunoglobulin IgM titer.In conclusion it could be concluded that the mixed culture of probiotic strains could increase the protective effects against S. aureus infection.

3. Studies on the antibacterial effect of probiotics and prebiotics against Staphylococcus aureus and Pseudomonas aeruginosa.
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