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Vol.6 No.3 – 3: Effect of Moringa oleifera leaves extract against electromagnetic field impairments on hemoglobin and testes of rat

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By: Aida, A.A *; Aziza A. Elsaeid * Shoman, H.M.** and Ola Mohamed Awad *

* Biophysics Department, Faculty of Science, Al-Azhar University, Cairo, Egypt

** Zoology Department, Faculty of Science, Al-Azhar University, Cairo, Egypt

Abstract

The present study has revealed the effect of Moringa oleifera leaves extract against electromagnetic field induced impairments. Forty-two adult white Albino male rats, weighting 150-180 g were involved in this study and divided into six equal groups. The first group was the control while the second group was daily supplemented with 200 mg/kg Moringa oleifera leaves extract orally for six days. The third group was exposed to an electromagnetic field of 1.5 mT, 50 Hz for 9 hours. The other three groups were exposed to an electromagnetic field of 1.5 mT, 50 Hz for 9 hours, and received the Moringa oleifera leaves extract in different supplemented ways. Blood samples were collected for the absorption spectrum of hemoglobin molecules analysis and serum total testosterone was studied. Samples of testes were taken for histopathological observations. The results showed that exposure of the animals to the electromagnetic field resulted in changing the absorption spectrum of hemoglobin, a highly significant reduction in testosterone level, and degenerative changes in testes. All these induced changes were decreased in groups treated by Moringa oleifera leaves extract in all ways. So through this study, one can conclude that damages induced by exposure to the electromagnetic field can be decreased by Moringa oleifera leaves extract.

Effect of Moringa oleifera leaves extract against electromagnetic field impairments on hemoglobin and testes of rat-converted (1)

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Vol.2 No.1 -4 : Ameliorating effect of propolis and moringa extract against equigan induced neurotoxicity and oxidative stress on rat hippocampus.

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By : Ehab Tousson, Ezar Hafez, Ahmed Massoud and Ahmed A. Elfeky

Abstract

In most countries worldwide, Equigan is anabolic steroid that is forbidden for human uses or for meat production. The present study was designed to investigate the ameliorating role of Propolis and moringa leaf extract (MLE) against Equigan induced neurotoxicity and oxidative stress on rat hippocampus. A total of 48 healthy male albino rats weighing 170-200 g and of 10-12 weeks age were divided into 6 groups (8 animals each). 1st Control group includes animals that injected intramuscularly with olive oil for 12 weeks. 2nd and 3rd groups were rats received Propolis and MLE respectively. 4th experimental group include animals that receive intramuscular injections of Equigan for 12 weeks; 5th and 6th groups where rats intramuscular injected with Equigan and treated with Propolis and MLE at the same time respectively. The obtained results indicate that hippocampal nitric oxide (NO), malondialdehyde (MDA), acetylcholine esterase (AChE) and total protein were significantly increased in Equigan group when compared with control group. In contrast hippocampal catalase, SOD and total thiol levels were significantly decreased in Equigan group when compared with control group. On the other hand hippocampal NO, MDA, ACE and total protein in Equigan group were significantly increased when compared with co-treated Equigan with MLE or Propolis groups. In contrast; hippocampal catalase, SOD and total thiol levels were significantly decreased in Equigan group when compared with co-treated Equigan with MLE or propolis groups. We can concluded that; MLE and propolis extract ameliorate the neurotoxicity and oxidative stress on rat hippocampus induces by Equigan.

4. Ameliorating effect of propolis and moringa extract against equigan induced neurotoxicity and oxidative stress on rat hippocampus.

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