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Vol.2 No.08 -5 : Specific learning disorders in epileptic children.

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By : Shewikar T. El-Bakry, Shaza M. Eltaher*, Abo Zaid A. Khodair, Khaled S. Meselhey

Abstract

Specific learning disorders are more common in epileptic children even with normal IQ, The Epilepsy related factors such as (duration of illness , type and severity of epilepsy and medications used ) are strongly related to increase risk of learning disorders. The present study is aimed to shed the light on the specific learning disorders in epileptic children and to study the relation between learning disorders and the epilepsy related factors such as duration , medications , type and severity of epilepsy. Also to study the relation between the learning disorders and the intelligence quotient.
The study was conducted on 60 children between the age group of 9and 12 years old.All were subjected to a Semi structured interview, Learning & Developmental Disorders Rating Scales ( LDDRS ) Battery (El-Zyat , 2007), Stanford-Binet Intelligence Scales (SB5), Fifth Edition translated by (Farag,2010).
The results showed that Seizures was not the only problem that children with epilepsy are suffering from but also they are at greater risk for developing learning Disabilities. From the developmental disorders attention disorder was the most common detected followed by memory then auditory processing disorder followed by visual processing disorder then motor skills disorders. While regarding the academic learning disorders reading disorder was the most prevalent followed by the writing and mathematics being the least detected among the studied group. It is concluded that the most leading causes for learning disability in epileptic children ,as verified in the studied

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Vol.2 No.07 -7 : Neurobehavioral disorders in a group of children suffering from idiopathic epilepsy.

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By : *Shewikar El Bakry;**Soha Abdel Hady Ibrahim ; Hasnaa Abdelrhman Abdallah

Abstract

Epilepsy is a common neurological disorder in which the normal activity of the brain cells is sometimes disturbed this can result in strange sensation, emotions and behaviors. The aim of the work is to study neurobehavioral changes that occur in group of children suffering from idiopathic epilepsy. This retrospective study included 80 children and adolescents, 50 of them with age range 2-6 years (28 males and 22 females, age 42.32±10.949 months) and 30 with age range 6-18 years (17 males and 13 females, age 9.57±2.369 years), enrolled from outpatient clinic of pediatric psychiatry& neurology Benha University Hospital.All patients were subjected to a complete history taking with stress on age of onset, duration of attack, character of

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Vol.1 No.6 -4 : Effects of L-carnitine and Ginkgo bilobaon cerebral cortex in experimentally-induced epileptic seizures disease in rat

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By : EhabTousson1;Mohamed F.F Bayomy2and BasiounyFouad El-sendiony٭2

Abstract

Pentylenetetrazole (PTZ) kindling is an acknowledged model for epilepsy and refers to a phenomenon in which repeated injection of this drug causes gradual seizure. The current study aimed to determine the possible protective and ameliorative effects of L-carnitine and Ginkgo bilobaleaf extracts (GLE) against PTZinduced epileptic seizures disease in rats. A total of 80 male albino rats were equally divided into eight groups; 1st group was the control; 2nd and 3rd wereGLE and L-carnitine groups, respectivel; while the 4th group was pentylenetetrazolerat groupand the 5th and 6th groups were pre GLE and L-carnitine groups respectively; the 7th and 8th groups were post GLE and Lcarnitine, respectively. PTZ leads to an increase in malondialdehyde (MDA), glutamate (Glu) and to a decrease in catalase, super oxide dismutase (SOD), glutathione peroxidase (GPx) activity, glutathione reductase(GSH), gamma amino butyric acid (GABA) and acetylcholine esterase (AChE) in the cerebral cortex of rats when compared to control group. Pre- and post treatment with GLE and L-carnitine were improved the biochemicalalterations in cerebral cortex that treated with PTZ.

4. . Effects of L-carnitine and Ginkgo bilobaon cerebral cortex in experimentally-induced epileptic seizures disease in rat.
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