By: Mabrouk A. Abo-Zaid¹, Ahmed H. Ismail¹, Ali H Amin^{2, 3}

1: Biology department, faculty of science, Jazan University, Jazan, Saudi Arabia

2: Deanship of Scientific Research, Umm Al-Qura University, Makkah, Saudi Arabia;

3: Zoology Department, faculty of science, Mansoura University, Mansoura, Egypt;

Abstract

COVID-19 pandemic disease has firstly occurred in Wuhan, Hubei, China. Then the infection spread globally. Many researchers now suggest the strong similarities of COVID-19 with the previous pathogenic human beta coronaviruses SARS-CoV and MERS-CoV. But there is limited knowledge about the immune response to COVID-19. So on the basis of the immune response of these viruses, we will try to predict how the immune system can deal with this infection. In this review, we focus on human coronavirus types and discuss current knowledge of immune response against SARS-CoV and MERS-CoV immune response, which may be helpful in offering the perspectives on immune responses against COVID-19.

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